SAMPLE ANALYSIS & QUALITY CONTROL

Our facilities offer a large spectrum of sample analysis services for quality control and characterization, ranging from simple DNA quantification to sequencing and miRNA profiling. Specialized in the optimisation and validation of sample testing methods, we provide methods, samples and data fit for your needs.

Ensure your samples are fit-for-purpose

Don’t waste precious material. Verify the quality of your samples and make sure they are suitable for their intended downstream purpose. Our scientific team has extensive experience, not only in executing quality control assays, but also in developing in-house quality control tools for all types of biological samples.

Get reliable, validated assay protocols

As one of few European biobanks, IBBL is an ISO 9001 certified and ISO 17025 accredited organisation compliant with the principles of NF S96-900 certification*, meaning that our assays are not only standardized, but also go through a formal validation process. In addition, we ensure the validity of the results we provide to you by regularly assessing the quality of our analysis methods through proficiency testing.

Make use of advanced technologies

Besides more traditional assays, we have invested in a number of advanced technologies such as meta-genomic sequencing or miRNA profiling to offer our clients a comprehensive range of services. For efficiency and speed, our assays have been implemented on high throughput platforms, allowing you to save time and costs.

Get customized assays

Our team of scientists and a dedicated project manager will work with you to tailor characterization assays to your specific needs, from the development to the production and validation of the assays.

Our Sample Analysis & Quality Control Services

QUALITY CONTROL AND CHARACTERISATION OF FLUID BIOSPECIMENS (serum, plasma, urine, CSF)

  • sCD40L measurement in serum
  • Creatinine measurement in urine
  • Cystatin C measurement in urine
  • Serum fingerprinting *
  • Haemoglobin measurement in serum and plasma
  • CRP measurement in blood
  • Calprotectin measurement in stool
  • LacaScore in plasma
  • IL-8 measurement in serum and plasma
  • IL-16 measurement in plasma
  • Fibrinogen measurement in serum and plasma

QUALITY CONTROL OF NUCLEIC ACIDS

  • DNA quantification by spectrophotometry
  • DNA quantification by spectrofluorometry
  • RNA quantification by spectrophotometry
  • RNA quantification by spectrofluorometry
  • Human DNA quantification (qPCR)
  • Bacterial DNA quantification (qPCR)
  • DNA cross-linking assessment by multiplex PCR
  • DNA fingerprinting
  • Long Range PCR
  • RNA integrity number (RIN) and DV200 measurement
  • Size range PCR
  • RT-qPCR for miRNA detection
  • SPUD assay
  • mRNA quality index
  • Illumina FFPE QC assay
  • cfDNA size measurement
  • WGA index
  • DNA integrity number (DIN) measurement

QUALITY CONTROL OF CELLS

  • Cell viability, apoptosis
  • Cell enumeration
  • Purity of cell subpopulations
  • PBMC functional assay (ELISPOT)
  • PBMC preanalytical score (IL-8, EDEM3)
  • Adipocyte functional assays
  • iPSC characterisation by immunofluorescence
  • iPSC characterisation by qRT PCR
  • iPSC characterisation by 3-germ layer differentiation

QUALITY CONTROL OF TISSUE

  • Histological QC (Tumour/stroma/necrosis)
  • snoRNA score assay (fixation time)
  • Cold ischemia score assay (ischemia time)

SAMPLE CHARACTERISATION

  • Sequencing (16S rRNA, TruSeq genotyping, HLA genotyping)
  • Methylation analysis
  • miRNA profiling (using high throughput Wafergen SmartChip™)

CUSTOMISED ASSAYS

  • ELISA
  • End-point PCR
  • Single and multiple qPCR (gene expression signatures)
  • Immunohistochemistry
  • Specific tissue staining
  • ddPCR

* coming soon

For more information, please download the specifications sheet below and/or get in touch with us.

Several countries across the world now offer attractive tax incentives for companies undertaking R&D activities and incurring expenditure on R&D-related activities. We invite our clients to consult the database developed by the OECD to find out how to claim for a tax relief on the costs for our services in their respective countries.

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